SME
Tissue Engineering · Problem type
Which bioreactor?
Use this for “Which bioreactor suits a thick bone scaffold, cartilage that needs loading, or fragile cell clusters?”
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Which bioreactor suits each tissue?
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Ask what the tissue lacks in a still dish: mixing, a gentle ride, flow through it, or load.
Assumptions
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Each bioreactor is matched to what the tissue needs most: mixing, gentleness, flow through the pores, or load.
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Medium that only flows around a thick scaffold feeds its outer layer; its middle starves of oxygen.
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Cells sense force: shear guides bone cells, and squeezing guides cartilage cells.
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